Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
Identifieur interne : 001023 ( Main/Exploration ); précédent : 001022; suivant : 001024Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
Auteurs : Wen Ling Wang [République populaire de Chine] ; Hui Juan Wang [République populaire de Chine] ; Yao Deng [République populaire de Chine] ; Tie Song [République populaire de Chine] ; Jia Ming Lan [République populaire de Chine] ; Gui Zhen Wu [République populaire de Chine] ; Chang Wen Ke [République populaire de Chine] ; Wen Jie Tan [République populaire de Chine]Source :
- Biomedical and Environmental Sciences [ 0895-3988 ] ; 2016.
Descripteurs français
- KwdFr :
- Anticorps antiviraux (sang), Anticorps neutralisants (sang), Chine (épidémiologie), Humains, Immunoglobuline G (sang), Immunoglobuline M (sang), Infections à coronavirus (sang), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Mâle, République de Corée (épidémiologie), Test ELISA, Traçage des contacts, Voyage.
- MESH :
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Antibodies, Neutralizing (blood), Antibodies, Viral (blood), China (epidemiology), Contact Tracing, Coronavirus Infections (blood), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Enzyme-Linked Immunosorbent Assay, Humans, Immunoglobulin G (blood), Immunoglobulin M (blood), Male, Republic of Korea (epidemiology), Travel.
- MESH :
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral, Immunoglobulin G, Immunoglobulin M.
- geographic , epidemiology : China, Republic of Korea.
- blood : Coronavirus Infections.
- epidemiology : Coronavirus Infections.
- transmission : Coronavirus Infections.
- Contact Tracing, Enzyme-Linked Immunosorbent Assay, Humans, Male, Travel.
Abstract
The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.
Url:
DOI: 10.3967/bes2016.027
PubMed: 27109133
PubMed Central: 7135062
Affiliations:
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Le document en format XML
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National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Hui Juan" sort="Wang, Hui Juan" uniqKey="Wang H" first="Hui Juan" last="Wang">Hui Juan Wang</name><affiliation wicri:level="1"><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; 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National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Gui Zhen" sort="Wu, Gui Zhen" uniqKey="Wu G" first="Gui Zhen" last="Wu">Gui Zhen Wu</name><affiliation wicri:level="1"><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; 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We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zaki, Am" uniqKey="Zaki A">AM Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S Van Boheemen</name></author><author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Liu, D" uniqKey="Liu D">D Liu</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Yi, L" uniqKey="Yi L">L Yi</name></author><author><name sortKey="Zou, L" uniqKey="Zou L">L Zou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petersen, E" uniqKey="Petersen E">E Petersen</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lan, J" uniqKey="Lan J">J Lan</name></author><author><name sortKey="Deng, Y" uniqKey="Deng Y">Y Deng</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Da Guan, W" uniqKey="Da Guan W">W Da Guan</name></author><author><name sortKey="Mok, Ck" uniqKey="Mok C">CK Mok</name></author><author><name sortKey="Chen, Zl" uniqKey="Chen Z">ZL Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Abdallat, Mm" uniqKey="Al Abdallat M">MM Al-Abdallat</name></author><author><name sortKey="Payne, Dc" uniqKey="Payne D">DC Payne</name></author><author><name sortKey="Alqasrawi, S" uniqKey="Alqasrawi S">S Alqasrawi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breakwell, L" uniqKey="Breakwell L">L Breakwell</name></author><author><name sortKey="Pringle, K" uniqKey="Pringle K">K Pringle</name></author><author><name sortKey="Chea, N" uniqKey="Chea N">N Chea</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Gao, J" uniqKey="Gao J">J Gao</name></author><author><name sortKey="Song, P" uniqKey="Song P">P Song</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Wang, Wen Ling" sort="Wang, Wen Ling" uniqKey="Wang W" first="Wen Ling" last="Wang">Wen Ling Wang</name></noRegion><name sortKey="Deng, Yao" sort="Deng, Yao" uniqKey="Deng Y" first="Yao" last="Deng">Yao Deng</name><name sortKey="Ke, Chang Wen" sort="Ke, Chang Wen" uniqKey="Ke C" first="Chang Wen" last="Ke">Chang Wen Ke</name><name sortKey="Lan, Jia Ming" sort="Lan, Jia Ming" uniqKey="Lan J" first="Jia Ming" last="Lan">Jia Ming Lan</name><name sortKey="Song, Tie" sort="Song, Tie" uniqKey="Song T" first="Tie" last="Song">Tie Song</name><name sortKey="Tan, Wen Jie" sort="Tan, Wen Jie" uniqKey="Tan W" first="Wen Jie" last="Tan">Wen Jie Tan</name><name sortKey="Wang, Hui Juan" sort="Wang, Hui Juan" uniqKey="Wang H" first="Hui Juan" last="Wang">Hui Juan Wang</name><name sortKey="Wu, Gui Zhen" sort="Wu, Gui Zhen" uniqKey="Wu G" first="Gui Zhen" last="Wu">Gui Zhen Wu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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